The first effort to sequence our genome, the Human Genome Project, took 13 years—an amazing feat, though not immediately relevant for patients. But now researchers from San Diego and Kansas City have made that leap, achieving genetic diagnoses in 26 hours—a new Guinness World Record.
This is a big deal. Many children born with genetic conditions wait years for answers. Infants with acute conditions can die before being diagnosed. Sequencing a sick kid’s genome—finding the genetic variants hidden in DNA’s four billion bases and quickly determining the significance of those variants—could provide crucial diagnostic information and drive life-saving treatments.
On April 25, National DNA Day, Stephen Kingsmore, president and CEO of the Rady Children’s Institute for Genomic Medicine, along with collaborators from Children’s Mercy Hospital in Kansas City and San Diego-based Illumina and Edico Genome, celebrated their world record at Rady Children’s Hospital. But the achievement means far more than international bragging rights.
“Diagnosing acutely ill babies is a race against the clock, which is why it’s so essential for physicians to have access to technology that will provide answers faster and help set the course of treatment,” said Kingsmore a few days before the ceremony.
The project, which was conducted by Kingsmore at Children’s Mercy, bested the team’s previous record of 50 hours. To shave off those crucial hours, the group used an Illumina sequencing machine optimized to move faster (kind of like putting a Tesla in insane mode). From there, the gene reads were put through Edico’s DRAGEN platform, which is designed to analyze genomic data.
The whole process took 26 hours from blood sample to initial diagnosis, results that could have a big impact on sick infants. In the original study, 65 percent of the diagnoses improved care.
But this was only one study on a handful of kids. The next step for Kingsmore and colleagues is to scale up the process so that every hospital NICU can take advantage of fast sequencing.
“I look forward to collaborating with both parties (Illumina and Edico) to implement this approach at Rady Children’s Institute for Genomic Medicine and ultimately neonatal and pediatric intensive care units across the country,” said Kingsmore.
The World Record That Could Save Lives
Stephen Kingsmore is the president and CEO of the Rady Children’s Institute for Genomic Medicine
Hatch
JUNE 18, 2021
3 Local Entrepreneurs Won a Startup Pitch Competition
The winners received more than $15,000 altogether for their businesses
By Marie Tutko
The founders of 11 small businesses competed in Union Bank’s fourth startup pitch competition on May 27, and three were awarded a total of more than $15,000 in funding. All the entrepreneurs are recent graduates of a business accelerator program hosted byConnect All @ the Jacobs Center, which is dedicated to minority-owned companies. Contestants completed a four-month training program, and then had just five minutes to pitch their ideas in a video presentation to a panel of judges. (Full disclosure: I participated as a judge in this year’s program.)
The first-place winner wasFirst Gen Scholars, a startup founded by Jonathan Burgos. First Gen Scholars’ mission is to help high school students who are the first person in their family to attend college—they not only assist with the college application process, but provide mentorship until the students graduate. Burgos won the $7,500 prize, and he also won this year’s Audience Choice award, which was decided by public vote through the Jacobs Center’s YouTube channel.
“Jonathan Burgosdid an outstanding job showcasing the importance of First Gen Scholars and highlighting the market opportunity and the long-term vision for the company,” said Bruno Rodriguez, Union Bank branch manager for the El Cajon Valley location and a judge on the panel. “Union Bank is proud to support the future of business in San Diego through this competition.”
The second-place winner wasCharbon Plus, founded by Lucien Eloundou, which produces skincare products for Black and brown skin. The unique ingredients for the charcoal mask are sourced from Cameroon. Eloundou won a prize of $5,000 to expand the line.
Taking third place this year wasHexagon Laser, a design and manufacturing company founded by Oscar Corral that specializes in artwork using laser engraving on wood. The company has created coasters and tap handles for local craft breweries such as Novo Brazil, and it also has a line of wall art and home decor. Corral won a prize of $2,500.
Jonathan Burgos, Oscar Corral, and Lucien Eloundou won the fourth Union Bank Start-Up Pitching Competition.
Hatch
JUNE 9, 2016
The Best Events at San Diego Startup Week 2016
From beer tech to the next big idea, here's something to do for everyone June 13-17
San Diego Startup Week is June 13-17
By Sanna Coates
This year’s Startup Week is jam-packed with events, spread out over 5 days and 10 different tracks. We have rounded up the best talks, panels, and parties for beer lovers, designers, tech geeks, and aspiring entrepreneurs.
Can you run a successful craft brewery in 2016 without solid tech integration? Find out what technology can do for San Diego beer at this Monday afternoon session.
Are you new to beer, or just want to refine your taste? TapHunter’s panel of brew experts are here to help! This session is guaranteed to have you thirsting for a cold pint afterwards.
Many successful San Diego breweries are already utilizing social media to create brand buzz and drive sales. Here they’ll be sharing all their secrets.
June 13, 10:45 a.m., 1 Columbia Place 24th Floor Room B
Ideas are crucial for anyone looking to get into entrepreneurship, but not all ideas are good ideas. The Lean Brand author Jeremiah Gardner can help you identify the bad ones early.
If the title wasn’t enough to get you intrigued, this session will include honest conversation on “the good, bad and ugly” with some top San Diego startup founders.
San Diego Startup Week is June 13-17. View the full schedule of events here.
The Best Events at San Diego Startup Week 2016
San Diego Startup Week is June 13-17
Hatch
APRIL 5, 2016
Things Will Be Great When You’re Downtown
A new data-mining project can help downtowns stay vibrant, and TwitchCon is moving to San Diego
Amazon-owned Twitch is moving its annual gaming convention, TwitchCon, to the San Diego Convention Center | Photo by f11photo / Shutterstock.com
By Mindy Tucker Fletcher
Follow the Money
A new report in The Atlantic CityLab by well-known urban studies guru Richard Florida puts San Diego at 7th on the list of Metro areas with the largest venture capital investment, ahead of Seattle. Topping the list are the obvious places such as San Francisco, San Jose, New York, and Boston. For San Diego, a town that is always lamenting the lack of venture funding, this may help dispel that thinking.
Move Over ComicCon, There Is a New “Game” in Town
Amazon-owned Twitch has just announced it is moving its annual gaming convention, TwitchCon, from the Marscone Center in San Francisco to more spacious digs at the San Diego Convention Center.
Twitch is the world’s leading social video platform and community for gamers. It boasts 100 million community members and 1.7+ million broadcasters per month, catering to the entire video game industry.
Last year’s convention—the inaugural event—brought 20,000 people to San Francisco. With an added day and the positive buzz surrounding the event and the move, they are expecting to top that number this year.
The event takes place September 30-October 2 and you can find the details here. Game on.
Hear Why One Startup CEO Moved His Business From SF to SD
Andrew Gazdecki, CEO and founder of Bizness Apps, penned this piece for TechCrunch about why he moved his San Francisco based mobile app builder business to San Diego. He makes a pretty good case. (Read a Q&A with Gazdecki here.)
Downtown, Things Will Be Great When You’re Downtown…
A new data-mining project out of the University of Trento in Italy might help shed some light on how to ensure a vibrant city. In her 1961 book, The Death and Life of Great American Cities, urban sociologist Jane Jacobs identifies four conditions that are essential for a vibrant city. Overall she argues a physically diverse city will flourish. Specifically, she says cities need the following four characteristics. First, the city must serve more than two functions so it attracts people with different purposes at different times of the day. Second, she recommends small city blocks that give people a chance to interact with each other. Third, the buildings must also be diverse with old and new to attract diverse economic groups. Last, it’s all density—of people and buildings. Until now there has been no cost effective way to test these ideas.
The new research has used technology to create a faster, easier way to analyze a city. By using OpenStreetMap, census data, land use data, and Foursquare data, researchers were able to prove that Jacobs actually knew what she was talking about. For downtowns striving to stay vibrant centers, like San Diego, this new research could help identify areas for improvement. I would love to see some of our local open data minds (I’m looking at you, Ben Katz) take this on.
Pivots and Opportunities
Reflexion Health, a digital health solution for physical therapy, has a new CEO. Replacing Spencer Hutchins who left in December is Dr. Joe Smith. Smith is moving to the streets of downtown from the Mesa, where he has been leading the health cost savings charge as the chief medical and science officer at West Health for the last several years. He recently stepped in as interim CEO at Reflexion and now has made it official. (Disclosure: this is my client.)
Entrepreneurs typically launch businesses because they’re passionate about a product or service, not because they want to manage its finances. While working to carve out a niche in their respective industries and drive their companies forward, many business owners find themselves bogged down by day-to-day accounting. Their existing accounting tools don’t provide the necessary visibility or insight, and they don’t have the time or resources to hire additional staff or a chief financial officer. That’s where NOW CFO comes in.
For more than 20 years, NOW CFO has been pairing businesses across the country with experienced accounting and finance professionals. Its outsourced model allows clients to customize solutions that match their individual needs, size, and financial challenges, whether that’s fractional or interim support, project-based services, or full-time placement.
NOW CFO’s clients range from startups preparing for rapid growth to established companies that need additional financial leadership without the commitment or expense of building an in-house team. However, many of these companies don’t fully understand their needs until they experience a “trigger” event: preparing for an acquisition or capital raise, navigating a first-time audit, or another period of transition. With a team of over 300 consultants nationwide, NOW CFO can start quickly and match the right expert to the right business.
“It’s important for companies to have financial visibility, and we can help them avoid a lot of the potholes that companies often run into,” says Mariah Block, a partner at NOW CFO’s San Diego branch. “Roughly half of our clients have an in-house finance person or department, and we’re resourced for more bandwidth when they need an extra set of hands at the staff or senior accountant level, or the controller or CFO level. Some clients use this a few hours a month and others use multiple people close to full-time. Our model is solution-based and customizable. We’re like a faucet you can turn on and off.”
With NOW CFO, there’s no one-size-fits-all approach. Solutions are based on the client’s individual goals, challenges, needs, and budget, meaning a client never pays for more than they need. Whether it’s a few hours of executive-level guidance or a full accounting team to support daily operations, NOW CFO meets businesses where they are and grows alongside them.
“We pride ourselves on providing our clients with the right resources at the right rate and being able to evolve as their needs evolve,” says Block.
And clients appreciate on-demand access to cost-effective support designed to improve performance and profitability.
Luxury car storage service Auto Concierge has partnered with NOW CFO to support growth over the past year. The arrangement began with a staff accountant who covered a leave of absence, but as the client’s needs changed, they also added a controller role. This allowed Auto Concierge to put effective processes in place and navigate operational challenges. Lori Church, Auto Concierge’s chief operating officer, says NOW CFO has been an “outstanding resource” and a “true strategic partner.”
“From the controller to the bookkeeper, every professional they’ve placed has brought a high level of expertise, responsiveness, and professionalism to our organization. Their team took the time to understand our business of high-profile clients and needs, adapted quickly to our fast-paced environment, and became a trusted extension of our team,” she says. “As Auto Concierge continues to grow, having a reliable financial partner like NOW CFO has allowed us to strengthen our financial and business operations while remaining focused on delivering exceptional service to our clients.”
The fan tweet seemed more fitting to Coachella than Scripps Pier. A selfie included a bearded man in the background: “The closest I’ll ever be to George Church #legend.”
George Church, right?! You know, professor of genetics at Harvard Medical School and serial entrepreneur. He helped invent genomic sequencing in 1984, created the Personal Genome Project and The Brain Initiative, cloned a woolly mammoth, co-founded nine companies.
So maybe Church doesn’t normally get the Mick Jagger treatment, but at the annual Future of Genomic Medicine Conference, geeks are revered.
Handicapping Genomic Progress
Hosted by Eric Topol and the Scripps Translational Science Institute (STSI), the conference was held on March 3 and 4 at Scripps Seaside Forum and offered a quick snapshot of genomic science: successes, shortcomings, ethical considerations and everything else. It’s about as inclusive as scientific conferences get. Researchers share the stage with MDs, entrepreneurs, policy wonks, technology gurus, journalists, and patients.
And there was plenty to discuss: the Cancer Moonshot; patient access to their own genetic data; incorporating genomic sequencing into daily care; crunching petabytes of data; and what to make of CRISPR, the revolutionary genomic editing technique that allows scientists to add or remove specific genes.
CRISPR was the cause célèbre at this year’s conference. The technique offers great promise and ethical pitfalls. Many rare diseases could be repaired with a single gene fix. On the other hand, the technique is a little Gattaca for some. One of the cool things about the conference is watching scientists work through these issues in real time.
With head-high surf pounding in the background, Soon-Shiong detailed plans to embrace immunotherapy against cancer. Rather than targeting the cancer, he believes we must target the patient, giving the immune system new tools to wipe out the disease. The Moonshot is a massive collaboration between researchers, drug companies, government agencies and others to share data and develop groundbreaking therapies.
George Church discussed more in 20 minutes than some people do in a lifetime: disease prevention, age reversal, gene editing. The buzz for his presentation was especially intense as one of his companies, Veritas, had just announced full genome sequencing and genetic counseling for $999, a new low.
Fan Base
The enthusiastic crowd included MDs, corporate and academic researchers, curious consumers and a high school group from Reno. Each year, science teacher Laurie Bissonette brings some of her brightest Sage Ridge High School students to the conference and STSI comps the fee—good job STSI.
The students prepare by reading some of the presenters’ research and sharing with the group. These kids are no joke. Senior Elyse Olesinski has her fingers crossed for Harvard and wants to be an oncologist and a bench researcher—attacking the problem from both sides. Junior Hunter Ferrel is looking forward to studying biology—it was her George Church tweet.
“I met George Church; that was the highlight of my trip,” said Ferrel. “He’s a legend; he’s my absolute role model. The research he’s doing in gene editing, it’s just so cool.”
La Jolla’s Geek Woodstock
The Future of Genomic Medicine Conference was held on March 3 and 4 at Scripps Seaside Forum
Hatch
MARCH 5, 2016
Last Chance on EvoNexus!
Top incubator looks for new companies
By Erin Chambers Smith
Super slick office space, mentorship and no equity stakes or fees taken by EvoNexus (thanks to support from corporate partners like Qualcomm, Viasat and Interdigital). Find more details here. If you have a company and would like to join the city’s top incubator, get moving. Deadline for applications is Monday.
Last Chance on EvoNexus!
Partner Content
JULY 10, 2026
Health & Wellness Summer 2026
It’s a Self-Care Summer. Because your best self is our favorite self.
If you’re anything like us, it can be easy to get so caught up in taking care of everyone else, that your own needs get lost in the ether. But while this may be a cliché, that doesn’t make it any less true: You can’t give your best self to other people unless you’re taking care of yourself.
Sometimes, that looks like stopping in for your regular acupuncture or chiropractic appointment. Other days, it means giving your body the fresh, organic fuel it needs to truly feel and function at its best. And some other times still, it involves leaving your responsibilities behind for a weekend to pamper yourself at an incredible resort and spa.
Only you can decide what your truly need. We’re just here to help you find the best ways to get it.
Tommy Bahama Miramonte Resort & Spa
Island living meets desert luxury at the Tommy Bahama Miramonte Resort & Spa in Indian Wells. When you step onto the 11-acre property, you’ll be surrounded by sweeping view of the Santa Rosa Mountains with olive trees and fragrant citrus groves decorating the grounds. In other words, everything about this relaxed but refined resort is primed to help you let go of the stress from home and enjoy easy sun-soaked days and gorgeous starry nights.
The rooms blend calming, woven textures with Tommy Bahama’s signature tropical prints and feature private lanais, making it easy unwind the moment you walk in the door. If you book one of the four Villa Suites, you’ll be treated to exclusive Tommy Bahama furniture and unique personal touches to further that feeling of instant ease.
At the award-winning Spa Rosa, the expert team will help reset and recharge your body and mind using methods and rituals inspired by the desert. The 12,000-square-foot retreat includes outdoor soaking pools, eucalyptus steam rooms, and outdoor cabanas, as well as massages, facials, and body masks—all aimed at creating a day dedicated to you. We’re particularly partial to the Day Long Escape, an indulgent all-day affair of CDBs soaks, renewing scrubs, life changing massages, and transformative facials.
Following your treatment, continue the experience with a meal on the patio at Grapefruit Basil. We love the Hamachi Crudo, a light, citrus-forward dish featuring premium yellowtail, house-made ponzu, creamy avocado, and fresh seasonal garnishes.
Whether you’re strolling the gardens, relaxing beside its saltwater pools, or indulging in a restorative treatment, you’ll be able to escape in style and relax in luxury at the Tommy Bahama Miramonte Resort & Spa.
Healcove Chiropractic
There’s no shortage of ways to stay active in San Diego—but if you really want to enjoy everything the city has to offer, you’ve got to make sure you’re giving your body its tune-ups. Enter: Healcove Chiropractic. The board-certified chiropractors and wellness professionals at Healcove are experts at addressing that stage where you’re not injured, exactly, but you’re not at 100%, either. Maybe you’re feeling a bit tense or stressed out. Or it could be that you’re not quite moving the way you want to. Sometimes, it’s just that the accumulation of days, weeks, or even years of daily strain is starting to take a toll. No matter what stage you find yourself at, the Healcove Chiropractic team can provide integrated, preventative care centered on long-term, science-backed approaches that ensure you can always stay active and live the life you want to live pain-free.
This starts by providing truly individualized care. Every patient can expect a thorough 60-minute consultation session that includes a posture and movement screening. This allows the team to develop a completely personalized plan. That plan might include chiropractic care, acupuncture, or massage therapy, as well as functional fitness training, vibration and sound therapy, and Dynamic Neuromuscular Stabilization, a clinical rehabilitation method that retrains the body’s stabilization systems. Whatever the team recommends, you can be sure that it’s tailored to meeting your body’s needs today and the future.
There’s a reason that San Diego Magazine named Healcove the “Best Chiropractor in San Diego”—don’t wait until you’re struggling with an injury to find out why. Book an appointment today for holistic, integrated care that helps ground and heal your body before it reaches a crisis point.
Juice Holler
West Coast wellness culture meets the community feel of Southern Appalachia at Juice Holler. Juice Holler’s menu consists of made-to-order smoothies and smoothie bowls, as well as grab-and-go cold-pressed juices, wellness shots, salads, and more. It operates from the blissfully simple premise that fueling up with food and drink that’s guilt-free and good your body should be simple, accessible, and, above all else, delicious. And if you haven’t yet made it out to the Encinitas café, which opened just this year, let us be the first to tell you: Juice Holler delivers on each and every of these fronts.
We love the Supercharger smoothie, a mood-lifting and body-fueling option made with banana, almond butter, blue spirulina, maca, grass-fed whey protein, raw cacao nibs, medjool dates, and coconut milk. We’re also partial to the Thrive Alive smoothie bowl, where avocado, mango, sea moss, spirulina, mint, coconut milk, and agave are mixed and topped with coconut, chia seeds, strawberry, mango, and chocolate drizzle. The wellness shots include the Detoxifier, a cleansing blend of kale, cucumber, lemon and spirulina, plus a shot specially designed to fight inflammation (named, fittingly, Anti-Inflammation). Probiotic overnight oats, lemon turmeric bars, and strawberry shortcake chia pudding are other standouts on the grab-and-go menu.
Much of the vibe feels beachy North County chic—think green tile with orange and pink accents, grounded with greenery and natural wood—but Juice Holler founder Kelly Sergott, a longtime Encinitas local, has also enfused the space with her Kentucky roots. In Appalachia, a holler is small valley between hills and mountains, where nature reigns, community is king, and nourishment comes right from the land. At Juice Holler, Sergott has created a holler for the busy modern times, using local ingredients to create a spot for people to come together and enjoy fresh, fast, feel-good fuel for their day.
Everwell Acupuncture
We’ve all had that experience with a medical professional where we’ve felt rushed, ignored, or misunderstood—and ultimately, like we didn’t get the answers that we needed. But at Everwell, the holistic acupuncture practice located in Solana Beach, the care team wants to transform your understanding of what healthcare can look like.
Patients at Everwell experience care rooted in intentional listening and radical empathy—and trust us, those aren’t just corporate buzzwords. This place actually puts those ideas into practice. You will always be given the time you need to tell your story— initial in-take appointments are two hours long—and you can rest assured that your story will be believed. Every single question and concern will be addressed by a dedicated practitioner who wants to find the specific solutions that work best for you, and you’ll receive care that’s aimed at healing the body, mind, and spirit.
Everwell’s highly trained, doctorate-level practitioners blend evidence-based acupuncture with the practice of classical Chinese medicine. (If you’ve never tried acupuncture before or aren’t sure if the team will be a fit, we’d highly recommended Everwell’s complimentary 20-minute consultations.) Research shows that by stimulating specific points on the body, acupuncture activates a natural healing response in the body, helping to restore balance, regulate the nervous system, and improve overall wellbeing. This allows the practice to address an incredibly wide range of conditions from chronic pain and autoimmune disorders to digestive issues, from stress and burnout to headaches migraines, fertility and postpartum struggles, hormonal imbalances, sleep concerns and more.
At Everwell, you can expect to feel heard, trusted, respected, and cared for. This is a space that doesn’t want to be just another healthcare provider you visit; it wants to provide patients with dedicated partner who will be there for their entire health journey.
