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Fore Genomics is helping parents detect which health risks their kids are predisposed to through newborn genetic screenings
If you were given the chance to see into the future, would you take it? For new parents Mandy and Morgan Moseley, the answer was yes. When their baby was just two months old, the couple turned to Fore Genomics for a glimpse of what might be on the horizon. “I have a lot of health issues in my family,” Morgan explains. “I wanted to see what was genetically passed down to my son.”
La Jolla–based Fore Genomics provides a genetic health screen for children that reports on more than 500 different conditions with pediatric onset, giving parents the opportunity to better understand their kids’ health. Humans have over 20,000 genes. By sequencing the whole genome—100 percent of the DNA—Fore Genomics can examine for variants in the genes to determine to which conditions an individual is predisposed. All it takes is a cheek swab.
“Your DNA can tell you if you’re at risk of developing disease later in life,” Matthew Pelo, Fore’s CEO and founder, explains. The test is designed for seemingly healthy children with no symptoms. With early detection, proactive decisions can mitigate health risks before issues even arise.
“Some diseases can be managed through diet, some through lifestyle. With others, you can take medication and potentially delay the onset of symptoms indefinitely,” Pelo says. Pre- and post-test counseling is included with the screening, so parents can be equipped with a tailored care plan for their little one’s health.
For the Moseleys’ child, the screening came up clear. “The only result they found was that ibuprofen isn’t going to work as well for him, which is a good thing to know,” Mandy says. “Babies can’t communicate when pain meds aren’t helping.”
Since Fore Genomics retests each year (a service included in the base price), they will know if any new red flags arise. “If something does come up, we are going to be ahead of it,” Morgan says. She is specifically on the lookout for diabetes, which runs in her family but often goes undetected. “My mom didn’t know she had it and almost died. That’s probably the biggest reason why I wanted to get him tested.”
Currently, the price tag is around $1,500. Pelo says the test cost over $10,000 when he originally launched it at a research institute in New York. He’d like to bring the price down even further, he explains, but it’s an expensive screening to run. Currently, this type of testing is not covered by insurance, so if parents are interested, they have to foot the bill themselves.

To some parents, like the Moseleys, the insight might sound priceless. To others, it could be a portal to a world of anxiety. To avoid stressful news with no course of action, Fore Genomics originally opted to report only on conditions with treatment plans. Pelo tells me that parent advocates pushed for more info. “Even if there’s no approved treatment option, there are still clinical trials, advocacy groups, Facebook groups. There are other ways to get involved,” he says. “Based on their guidance, we’ve expanded what we screen for.”
Genetic testing is not a rare occurrence. Almost every newborn in the US undergoes a state-mandated genetic screening—in California, it covers 80 conditions, including sickle cell disease and rare metabolic disorders. Fore Genomics goes further, testing for hundreds more conditions. “We’re basically newborn screening on steroids,” Pelo says, adding that Fore’s is currently the most comprehensive test that can be done on a child. “We want to give parents access to more information.”
This type of testing differs from NIPT (non-invasive prenatal testing), which screens for conditions in the womb. “There are a couple of companies expanding what can be done [with] NIPT,” Pelo says. “But even then, there are a lot of concerns on what you can and should be reporting on.” Disability advocates have questioned the ethics of terminating a pregnancy based on genetic complications, drawing parallels between NIPT and eugenics. The Fore Genomics Genetic Health Screen is designed for newborns, infants, and children under the age of 5. “The child is already here,” Pelo says. “We want them to live the healthiest life possible.”
A major concern raised by direct-to-consumer DNA tests is data privacy. Companies like 23andMe or Ancestry.com utilize DNA for genealogical purposes, which exempts them from being HIPAA-compliant. Since Fore Genomics uses genetic testing for health and medical reasons, the company still falls under HIPAA and cannot disclose an individual’s health information without consent. However, even under HIPAA, a genetic testing company can sell your data—as long as it’s stripped of any identifying details. According to Pelo, Fore doesn’t do that. “We take data privacy and security very seriously,” he says.
Fore Genomics has to think about the child’s consent, as well. The company only screens for conditions with pediatric onset—not diseases that may arise later in life, like Alzheimer’s or ALS, even though that information is available in the genome. Pelo says it’s up to the child to decide whether they want that knowledge when they come of age.
How long does Fore Genomics hold onto an individual’s sequenced DNA? “Potentially forever,” Pelo says. “The DNA you’re born with is the DNA you die with. So, sequencing at birth can potentially tell you stuff 40 or 50 years later.”
Mandy and Morgan Moseley’s son is now 10 months old, and they are expecting a baby girl in 2025. They intend to order a Fore Genomics genetic health screen for her, as well. Many of the conditions in Morgan’s family predominantly affect women, and Morgan herself has a blood clotting disorder, as well as fertility challenges and Hashimoto’s disease. “Men don’t usually have thyroid problems or issues with fertility,” she says.
“Knowing that she’s going to be female, I’m more excited to get her tested.”
Cora Lee was born and raised in San Diego. More of her work can be found at coralee.net.
Through its Playmakers initiative, San Diego FC is working with artists, musicians, and other local creatives to shape the identity of the city’s newest professional sports team
What does a soccer team have to do with San Diego’s arts scene? Quite a lot, as it turns out. When San Diego FC launched, the club could have spent its marketing budget on billboards, bus wraps, and digital ads. Instead, it went into neighborhoods, found local artists and creatives, and started building the club’s identity with them. Through its Playmakers initiative, artists have designed limited-edition merchandise, had their work featured on the stadium’s jumbotron, and found themselves in front of thousands of fans—and, in some cases, a national TV audience.
For this special edition of the podcast, created alongside San Diego Magazine’s September arts and culture issue, host Troy Johnson talks with Sebastián Morúa, SDFC’s Senior Vice President of Brand & Innovation, and longtime San Diego native and creative Tony Martinez of Barrio Junto. The conversation gets into why a professional soccer club would make local art part of its business, how Martinez’s decades in San Diego’s creative community helped shape Playmakers, and the club’s early efforts to connect with artists across the county through its Chrome Ball Tour and neighborhood events. The goal, they explain, isn’t simply to put a local artist on a T-shirt. It’s to let the people who already understand San Diego help define what the new club looks and feels like.
The conversation also gets into the less glamorous—but important—side of supporting artists: money. They talk about how Playmakers pays local creatives, the value of the platform SDFC provides, and what it means to build an ongoing relationship between a professional sports club and the artists who help shape its identity. They also discuss the club’s growing music initiative, which will bring local musicians into the fold, and the many ways artists have already contributed to SDFC through merchandise, murals, Parks & Pitches projects, and more. Ultimately, it’s a conversation about soccer, art, community, and what can happen when a major sports franchise gives the people already making culture in San Diego a bigger platform.
This summary was provided to you by AI. To hear from the humans, listen to the podcast wherever you get your podcasts.
Chef collaborations, cooking demonstrations, DJs, games, photo ops, and plenty of reasons to keep wandering on Oct 3 and Oct 4
At Del Mar Wine & Food Festival’s Grand Tasting, the walk between food tents can take a while. You might stop to watch a chef competition, get pulled toward the DJ, or find yourself playing mini golf before you remember which bite you were after.
Across the Del Mar Polo Fields, there’s also line dancing, a 1961 red Beetle ready for photos, and an aviation-themed pop-up with Reno Tahoe chefs and mixologists. Need a slower stretch? Check out the wellness stops or browse the shops. Here’s what to look for as you make your way through the festival’s zones:

VIP ticket holders get a head start, with the VIP Reception running from 11:15 a.m. to 1 p.m. and serving first bites, first sips, and a few surprises before the Grand Tasting officially gets going. Champagne Telmont will make the festival’s first pour, while Cohn Restaurant Group brings carajillos alongside pours from Karl Strauss, Licor 43, Tap Truck San Diego, Bebemos Tequila, and Devil’s Grin Gin.
The bites are just as good. Celebrity chef Beau MacMillan will serve a first bite, while Warung RieRie is bringing one of its highly coveted dishes. Yes, this is the restaurant that currently has an eight-month waitlist. You’ll also find bites from The Shellfish Affair, The Waverly, Wolf in the Woods, Dora Ristorante, Cori Pastificio Trattoria, An’s Gelato, Pacific 333, Vintana, and more.
And because every good first act needs a soundtrack, there will be live painting and music, with Courtney Govan bringing live jazz to the reception. It’s the perfect opening act before the main event.
During the VIP Reception, chefs Tommy Gomes and Jeff Roberto will conduct a live ahi cutting. Plant Paradise brings another culinary angle, with celebrity chef Zuliya Khawaja joining the plant-based lineup. The area combines chef talent with plant-forward restaurants and brands, giving guests a chance to see just how creative plant-based cooking can get.
Throughout the weekend, The Stage keeps the cooking demonstrations coming, with celebrities and chefs sharing techniques, recipes, and plenty of inspiration for anyone who plans to actually cook something when they get home. Before you know it, you’re watching a chef demo, casting your awards vote, and sipping mezcal on the grass with friends you just met in line.

At the Grand Tasting, dancing just sort of… happens. A DJ drops the right song. Someone’s holding a taco in one hand and a glass of wine in the other. The country zone breaks into a two-step. Friends convince friends. Strangers become temporary dance partners. By the end of the day, everyone’s forgotten they were ever worried about looking cool.
DJ TENAX will be spinning in Plant Paradise, bringing house, techno, and UKG to an open-air dance floor that’s hard to leave. Chris Cantore, a veteran San Diego broadcaster, takes over the VIP Tent, while BootScootin Line Dance and PVO Events bring country-style line dancing to the Polo Fields, so you can work off your tasting itinerary one two-step at a time.
Then a live guitar hum in the distance leads you to a fuchsia boa over at the Pride Zone, where you’ll find yourself covered in sequins and having the lawn party of a lifetime.
Not every activity at the festival requires a tasting glass (although it’s certainly encouraged).
The Matchday Experience brings San Diego FC and San Diego Wave FC into the Grand Tasting, complete with interactive tents and plenty of game-day energy. Athletic Brewing is also sharing activation space with San Diego Wave FC, bringing a fun nonalcoholic option into the mix.
For golf fans, the Los Angeles Golf Club is bringing a Dryve Box golf simulator to the festival. And if your competitive streak is less fairway and more miniature windmill, SD Pop Up Mini Golf has you covered.
The Beach Zone gets in on the action, too, with surfing-inspired elements and Playavole paddle courts. Hemlock Hats and other California brands add to the coastal atmosphere, but the real draw is having somewhere to actually play. And don’t worry, you can cool down in COOLA’s turquoise beach chairs, too, and when your bestie suggests reapplying sunscreen, obviously you do. Basically, there are plenty of ways to work up an appetite between tastings.

You’re going to want to take photos, and the festival has made that extremely easy.
A Timeless Day is bringing multiple photo moments to the Grand Tasting, including a 1961 red Beetle at The Italian Getaway and a teal VW bus in The Beach Zone. For something a little more polished than the standard group selfie, head to the Locals Zone for Pixster Photo Booth and San Diego’s version of a Glam-Bot, complete with a grass red carpet.
Bebemos Tequila is also bringing back its festival-favorite hidden speakeasy. If there’s ever a time for a photo, it’s here. Otherwise, people might not believe you. The speakeasy serves bone marrow shots straight from the bone, with candlelight, a lounge area that makes it hard to believe you’re in a tent outside, and little orange shot glasses. This is “first slide of your festival photo dump” material.
You can also grab your squad and head to LaCroix’s bright and ridiculously cute setup, or swing by San Diego Magazine’s area, where you might stop for a photo in front of the larger-than-life SD Magazine sign and find yourself watching a painting come to life.
But really, you’re in Del Mar. The ocean is essentially your backdrop, and every zone gives you an excuse to stop for the obligatory “totally candid” photo. And yes, the best strategy is to get the group shot before everyone has been sampling wine for three hours.
The Grand Tasting also doubles as a little shopping excursion, with local makers, fashion, vintage finds, jewelry, and lifestyle brands scattered throughout the grounds. Smoke Revival Vintage Vault brings the thrill of vintage treasure hunting, while Nortte Hats and Hemlock Hat Company make a pretty good case for leaving with a new accessory.
Keep an eye out for jewelry and creative vendors, too, including Iris Studio Jewelry and New Nightfall Jewelry, plus local artists and makers featured throughout the festival.
You can come for an all day food and wine festival, but still leave with something shiny you definitely did not plan to buy.
We know, at some point, even the most dedicated grazer has to come up for air. The Novo Dia Wellness Zone is designed for exactly that, bringing together mocktails, coffee, hydration, wellness brands, and even bites from Parakeet Cafe.
Step away from the food and drink frenzy for a few minutes, relax in the shade, try some skincare, stretch with prAna, and maybe grab some Instant Hydration Electrolytes before round three.
There’s also nothing wrong with stopping to smell the roses at Green Air Botanicals while devouring a dairy-free cheese dip. It’s less about disappearing from the party and more about making sure you have enough energy to keep going.
The zones give you somewhere to wander, and the activities give you a reason to keep going. So grab your tasting glass, check the schedule, and leave a little room in your afternoon for something you didn’t plan on doing. At Del Mar Wine & Food, that’s usually where things get interesting.
Isabella Dallas is a freelance writer for San Diego Magazine and the Arts and Culture Editor at The Daily Aztec in her final year at San Diego State University. She previously worked as an editorial intern for SDM, but when she’s not writing, you can find her trying the best coffee spots in SD, devouring the latest rom-coms, and indulging in anything and everything pop culture.
A century ago, there was a stage actress known as San Diego’s Sweetheart—we traced her footprint through history, up to modern day
There was once an actress known as “San Diego’s Sweetheart” who mailed herself to Los Angeles—donning a helmet covered in postage stamps and boarding a two-seater, single-engine mail plane. The publicity stunt was billed as the first air parcel package in the US. It wasn’t. She wasn’t even the first human to be mailed: When the US parcel post started in 1913, at least seven people mailed their newborns to relatives (an innovative loophole eventually outlawed).
Technicalities be damned. That kind of nose for spectacle was why Virginia Brissac was such a star—landing bit parts in TV shows (I Love Lucy, Dragnet) and 155 films, notably playing James Dean’s grandmother in Rebel Without a Cause. “Nobody could help but love her,” her dresser told San Diego Magazine in a 1971 feature, published when Brissac was 88 years old.
In 1911, she topped the Playbill at the opening of the Savoy Theatre at 3rd and C streets in Downtown—a grand live-performance hall built for $150,000 ($5.2 million in today’s money). It became one of the premiere vaudeville theaters in the country (under vaudeville king Alexander Patages). The theater helped make San Diego a destination for stars like silent-film comedian Roscoe “Fatty” Arbuckle, heavyweight champ Jack Dempsey, plus classical legends Rachmaninoff and Anna Pavlova. As theaters converted to movie houses through the ’20s and ’30s, the Savoy remained dedicated to live humans. It closed in 1940, and the Civic Theater now stands in its footprint.
As for Brissac, during a time when women couldn’t even vote, she led a stock company under her own name at the Strand Theatre. The Brissac Company held a four-year residency, “an all-time successful record run for San Diego,” the article says. That classic Ocean Beach theater (featured in San Diego film legend Cameron Crowe’s Almost Famous) has been closed for decades, its bones now a chain beachwear and souvenir store. But Brissac’s legacy lives through the women leading San Diego’s theater scene.
Read the entire 1971 article by Merle Clayton below…











Emma Veidt is an editor at San Diego Magazine. She earned her bachelor's and master's degrees from the Missouri School of Journalism. She loves running, hiking, and rock climbing, but really, she mostly loves encounters with the street cats around North Park.
KQ Aesthetic Society goes beyond cosmetic to provide comprehensive care and transformative results
Kelly H. Harfouche, founder of KQ Aesthetic Society, knows firsthand that cosmetic treatments like fillers, neurotoxins, and microneedling, can not only enhance a person’s appearance and restore confidence, they have the power to truly change a person’s life. An expert injector has the ability to tailor treatments to each individual patient’s anatomy and goals for personalized results. Harfouche, a board-certified nurse practitioner, has spent nearly a decade perfecting her craft as an aesthetic injector and integrating her multifaceted artistic skills with precision patient care. Her commitment to continual education and training, plus a passion for helping people look—and feel—their best, set KQ Aesthetic Society apart in a sea of local medspas.
For many people considering nonsurgical treatments, the intent is to look refreshed and refined. KQ Aesthetic Society’s philosophy eschews a cookie cutter approach that bases treatments around units, instead working to understand each person’s unique goals, then curating a treatment plan to fit that vision. Harfouche focuses on “inclusive luxury,” the belief that everyone deserves access to aesthetic treatments, respective of budget restrictions. She develops long-standing trusted relationships with her patients, and works with each one to achieve their aesthetic objectives and address the underlying causes of their concerns.
“For me, forming an honest and open relationship with every patient who walks through the door is essential. This means understanding them on a deeper level and meeting them where they are to define and achieve their individual goals,” she says.

Drawing on her artistic background, which inspired her transition into medical aesthetics, Harfouche sees each client as a “unique canvas.” Rather than relying on standardized procedures, the practitioner’s distinctive approach combines her profound understanding of the physiological and anatomical changes associated with aging with an unwavering commitment to ongoing education about the newest products and their mechanisms of action. Her goal is to make each patient feel beautiful in their own skin and to embrace their individuality.
She has also pioneered a way to combine her talent for aesthetic artistry with her philanthropic nature. Harfouche is one of only a handful of providers using dermal fillers to treat patients with lip asymmetry and scarring resulting from cleft lip surgery. Patients travel from around the country for this transformative treatment, noting increased confidence and a restored identity. She hopes to eventually launch a training program to help fill the void in this space.

“My passion has always been connecting with people and giving back in any capacity that I can,” she says. In the rapidly advancing landscape of aesthetic medicine, you can place your confidence in Harfouche and KQ Aesthetic Society to deliver exceptional care. To learn more or book a consultation, please visit kqaestheticsociety.com.
Jonathon Glus on the Art + Design District, investing in the creative economy, keeping artists in the city, and what we can learn from places like London and Chicago
Jonathon Glus is the Prebys Foundation senior fellow leading the development of the Art + Design District at the Downtown San Diego Partnership. He has been asked what an arts and design district is many times. In our conversation, I asked him instead to describe what it isn’t. His answer opened up a broader discussion about what San Diego has and hasn’t invested in, what it has the capacity to become, and what other cities have done that we haven’t. Glus speaks about global art fairs and architecture biennials in Chicago and long tables at dinner parties all with the same fluency. He also discusses who gets to live in the neighborhoods where creative work happens, and what it means when they can’t afford to stay.
Jonathon Glus: It is not a place designed intentionally and specifically for tourists. Of course there will be opportunities for tourists to come, but the district is really focused on creatives, on creative education, and on the creative workforce—as well as our major performing arts organizations. That is the emphasis.
[It needs to] develop greater connectivity between the anchor institutions—the symphony, Broadway San Diego, the opera, all the wonderful things happening in Balboa [Park]—and the creative workforce that will be living and working in that neighborhood 24/7.
We have not been intentionally investing in the contemporary art product that other major cities have been building. A contemporary art fair. A biennial that reflects the ethos of this region. Chicago developed an architecture biennial about eight years ago. London has a design biennial. Desert X, right here in Southern California, invests in and elevates contemporary artists inside a city. We have not really been playing in the global art market in a way that we have the capacity to.
We have a wonderful foundation. Two theater companies that produce work that goes to Broadway more than many regional theaters in the country, major museums, artists teaching at UC San Diego and University of San Diego. What a city does when it wants to take itself to the next level is intentionally create the product. Miami went after the Art Basel fair; they did not passively receive it. You have to have the intention and the will, and you have to go after it. We haven’t done that in the way that other cities have.
Look at what we did with the tech sector; we’re now a major tech center. That was intentional. Leadership organized around it. We have to do the same thing around the arts. We have a lot of contemporary art collectors here. We have a lot of galleries. But the ecosystem of the business of contemporary art is not as organized or as visible as it should be.
It’s bits and pieces of different cities. Dubai has invested very quickly and very intentionally in contemporary art—art fairs, design fairs, higher education, artist residencies from all over the world. London has centered artists and creatives in the contemporary zeitgeist in a way that was not true 40 years ago. They built biennials. They ensured British artists had affordable housing and workspace. They made sure the media paid attention to what they were doing.
If you don’t have an artist at your dinner table, it’s not a dinner party. That sounds elitist, but it’s true. It shows the value that artists have in a community. Our relationship culturally with Tijuana is really significant here because artists in Baja seem to be at the table.
They aren’t. When super creative people are in a community doing extraordinary work, that draws other super creative people doing extraordinary work. That’s why other arts and design districts around the world end up populated with some of the most interesting restaurants and young fashion designers. Creatives want to be around other creatives.
Our creative economy already employs about 170,000 people and generates more than $11 billion in economic activity. It’s large and robust. But we must center all of this in accessibility and affordability. Williamsburg used to be affordable. Artists can’t afford to live there anymore. Wicker Park and Bucktown in Chicago—artist central, now unaffordable. If we’re going to invest in this district, we have to be really intentional about housing and workspace, so creatives have a place in the future of this district.
I think the lesson is that nothing changes. What do people love? Long tables. Why? Because you’re with a lot of people—some you may have known your entire life, but most you don’t. And if it’s driven by a creative process, all the better. We know one of the best ways to do that is around food, but also music.
For the Art + Design District, part of why we’re leaning into the process is because, culturally, we’re bringing down the barriers between film, fashion, multimedia, tech, and architecture. It’s an experiential mashup in the best possible way.
And it’s not just about art and design, but community writ large. Creative expression is something we all desire. Whether it’s at a long table, at the opera, or in your studio, we gravitate toward creative expression as a way of building community and communicating with the people around us.
I hope you are writing about this in seven years when the district is fully mature. But this is just the beginning for all of this. I think that’s what’s most exciting to me. We don’t know what this is going to be like, but we know it’s going to be creatively centered, and that’s super exciting to me.
Whether you're a lover of the arts, music, or a leisurely stroll through the park, these are Balboa's best attractions
On February 28, 1926, the Fine Arts Gallery of San Diego (now called the San Diego Museum of Art) opened its Plateresque doors to 3,000 guests for opening day. Over the next century, the museum changed with the times—even once functioning as a naval hospital after Pearl Harbor. This year, the museum is celebrating its 100th birthday with an exhibit (open through January 24, 2027) featuring photographs, ephemera, and film footage spanning the museum’s history.

Every Sunday from 2 to 3 p.m., stop by the historic Spreckels Organ Pavilion for a free concert presented by the City of San Diego on the largest outdoor organ in the world (more than 5,000 pipes). The pavilion seats 2,400 for performances by the civic organist or guest artists.
Some think natural history museums are just cemeteries for dioramas that haven’t received an update since the Reagan administration. When it comes to The Nat, which just finished a $7.5 million rejuvenation, they’re totally wrong. The museum debuted a new rooftop that replaces its 25-year-old atrium. The old roof created a greenhouse effect that steamed up some exhibits, so the new one—which includes 200 solar panels and better temperature control—will help preserve the artifacts inside. Each Friday in the summer, The Nat also becomes one of the season’s vibiest hotspots during Nat at Night, with food from places like Wolf in the Woods and The Craft Taco, bars and signature cocktails on several floors, and a rooftop DJ.
The Fleet Science Center just received its most significant update since the 1990s. It expanded its exhibit space by 20 percent and introduced a newly designed entrance gallery (formerly the IMAX theater lobby) that includes free exhibits for visitors who want a taste of the science without paying an admission fee. The former ticketing area now houses the Mindbender Mansion exhibit, and there’s a new café, Element 8, that will, of course, sell the center’s famous soft serve.
A look at San Diego's top designers creating unique environments that combine creativity and function















AVRP Studios’ tradition for Design Excellence and Innovation began in 1976 with Doug Austin, FAIA, in Solana Beach, California. The firm has since grown to complete major projects throughout the United States and Canada. We think of ourselves as a family and we care deeply about people. We want to inspire, help make their lives richer and more complete through our efforts. We believe that architecture is one of the most important art forms because of the impact it can have on the lives of those it touches. We’re delighted to have been recognized with over 150 awards for design excellence.
703 16th Street, Suite 200, San Diego, California 92101 | 619-704-2700 | avrpstudios.com