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Features SEPTEMBER 30, 2022

Treatments on Trial

San Diego is a hotbed of medical trials, which often unearth the future of medicine. Here are the big ones being tested right now.

Treatments on Trial
Illustrations by Ileana Soon
clinical trials

clinical trials

Illustrations by Ileana Soon

For those with an arm or a mouth to spare, San Diego scientists are in need. They’re armed with pills and injections that may contain the future of healthcare, the big breakthrough. They may protect people from a virus like Covid-19, treat a disease such as diabetes, or offer insight into the next steps toward a cancer cure.

“The advances of tomorrow will come from clinical trials being conducted today,” says Dr. Thomas Buchholz, chief scientific officer at Scripps Health. This city is a hot spot for clinical trials, a vital component of medical research. At least 2,400 are currently underway in the San Diego region, testing treatments for conditions ranging from psoriasis to phantom limb pain. That’s 7 percent of all active clinical trials in the nation.

“San Diego has a robust portfolio of trials, largely due to the excellence of our health care systems and the strength of our scientific and biotechnology communities,” says Dr. Buchholz. In fact, pharmaceutical companies turned to hundreds of San Diegans to test five Covid-19 vaccines that are now authorized for use around the world: Moderna, Pfizer-BioNTech, AstraZeneca, Johnson & Johnson/Janssen, and Novavax.

Being a part of the future has its pros and cons. Subjects often get paid, and they may gain access to cutting-edge treatments. But experimental medications may not work as well as existing drugs or cause serious side effects. In many trials, some patients get placebos instead of real medications. This is a routine part of the process to determine whether there’s any benefit to the drugs, but it may leave sick patients without a treatment that turns out to be effective.

Despite the risks, clinical trials attract participants who hope to help usher in a healthier future. And in some cases, clinical trials are the best option for patients with life-threatening diseases. “Some cancers become resistant to the standard approaches, and clinical trials can offer the greatest hope in this setting,” says Buchholz.

Here’s a look at several important clinical trials that are underway in the San Diego region.

Breast Cancer

Can Radiation Treatment Be Shortened?

Scripps MD Anderson Cancer Center is testing whether it’s feasible to adjust the time that certain breast cancer patients require radiation. Subjects will receive the same cumulative radiation dose, but they’ll be randomly assigned to get it over 3 or 5 weeks. Researchers will study how the patients fare and explore whether the shorter treatment period improves their quality of life.

Atrial Fibrillation

Could Surgery Be a Good First Treatment?

People with atrial fibrillation, a kind of irregular heartbeat, typically start treatment by taking blood thinners to prevent clots. But blood thinners can cause bleeding and bruising. At Sharp Chula Vista Medical Center and Scripps Memorial Hospital, cardiologists are recruiting patients to undergo implantation of a Watchman FLX left atrial appendage closure device as a first-line treatment. The device prevents blood clots from escaping a part of the heart where they may form between heartbeats.

Depression

Can Brain Therapy Help Patients Who Can’t Feel Pleasure?

Patients whose depression doesn’t respond to medication often turn to transcranial magnetic stimulation (TMS), in which short magnetic pulses stimulate nerve cells. UCSD is testing TMS in patients who have depression with anhedonia—an inability to feel pleasure. The goal is to expand personalized medicine, in which patients get treatments that are the ideal options for their specific conditions.

Long Covid

What Does It Mean for Kids and Young Adults?

Rady Children’s and UC San Diego are working to understand how long Covid—wide-ranging symptoms including fatigue, joint pain, headaches, “brain fog,” fever, shortness of breath, anxiety, depression, chronic cough, sleep problems, and more that last beyond infection—is affecting children and young adults up to age 25. The study also hopes to identify more concrete risk factors for developing the condition, the incidence of which is not currently known but is estimated to occur in about 10-30% of people who have had acute Covid-19 infections. Participants do not need to have had Covid-19 or suffered long-term effects after infection to participate in this $1.5 billion, four-year-long nationwide study that is in part funded by the National Institutes of Health.

Exercise

Will Trolley Access Boost Public Health?

UCSD is tracking 465 people who work on the La Jolla campus for over two years in the wake of the opening of a new San Diego Trolley station. The researchers expect they’ll find that access to public transit improves health by boosting well-being, lowering depression, and improving quality of life.

Top Doctors

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Features OCTOBER 10, 2022

San Diego’s Top Doctors 2022: The List

The annual list is chosen by SDCMS and voting physicians who refer those within and outside of their specialty

San Diego’s Top Doctors 2022: The List
faces of healthcare, spine institute

Front row, left to right: Paul D. Kim, MD, Ramin Raiszadeh, MDBack row: Stephanie Haua, PA-C, Josephine Turner, Administrator, Sophea Bergen, PA-C, Davina Lam, PA-C 

For almost two decades, the San Diego County Medical Society (SDCMS) has worked collaboratively with San Diego Magazine to recognize physicians who are held in the highest regard by their peers. Votes and nominations are open to all physicians in San Diego. The voting physicians are asked to vote for physicians within and outside their specialty to whom they would refer their friends and family. Through this process we have identified 747 physicians in 98 specialties.In a synchronized effort, SDCMS confirmed every individual nominee’s Medical Board of California licensing and current practicing status. Through this exhaustive process, 747 physicians are being honored this year. Many of them have also been recognized for multiple years since we began publishing this list. (These physicians have the number of years they have been selected listed in brackets behind their name.)I must point out that many superb physicians are not represented on this list. The selection criteria are strict, with only a few percent of physicians selected in each specialty. Many physicians received multiple votes from their peers but did not reach the threshold to be on the list. The best choice of physician for a patient should include many factors. All physicians in San Diego work collaboratively to provide the very best care for all of their patients.We welcome and encourage all San Diego County physicians to participate in their county and state medical societies as we work toward the SDCMS vision: “Physicians United for a Healthy San Diego.” We appreciate the assistance of all of the physicians who voted, and we thank San Diego Magazine for their support.Congratulations to all of our 2022 Top Doctor selectees,Toluwalasé (Lasé) Ajayi, M.D.President 2022-2023, San Diego County Medical Society


Top Doctors 2022

* Brackets denote the number of years chosen as a Top Doctor

ABDOMINAL SURGERY

Mark Christopher Takata, MD [7]Scripps Clinic Medical Group
10666 N Torrey Pines Rd, MS 213
La Jolla, CA 92037
(858) 554-8984

 

ADULT CARDIOTHORACIC ANESTHESIOLOGY

Dalia Abadeer Banks, MD [4]

UC San Diego Health

9500 Gilman Dr, MC 0898

La Jolla, CA 92093

(858) 657-6510

 

Alexander M Girgis, MD [1]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 534-8930

 

Timothy Michael Maus, MD [3]

UC San Diego Health

9500 Gilman Dr, MC 0898

La Jolla, CA 92093

(858) 657-6510

 

ADVANCED HEART FAILURE AND TRANSPLANT CARDIOLOGY

Peter Maclean Hoagland, MD [12]

San Diego Cardiac Center

3131 Berger Ave, Suite 200

San Diego, CA 92123

(858) 244-6800

 

Brian E Jaski, MD [17]

San Diego Cardiac Center

3131 Berger Ave, Suite 200

San Diego, CA 92123

(858) 244-6800

 

Hirsch Sumir Mehta, MD [5]

San Diego Cardiac Center

3131 Berger Ave, Suite 200

San Diego, CA 92123

(858) 244-6800

 

Justin Thomas Parizo, MD [1]

San Diego Cardiac Center

3131 Berger Ave, Suite 200

San Diego, CA 92123

(858) 244-6800

 

Marcus Anthony Urey, MD [1]

UC San Diego Health

9300 Campus Point Dr, MC 7411

La Jolla, CA 92037

(858) 657-7000

 

ALLERGY AND IMMUNOLOGY

Andrew Allen White, MD [5]

Scripps Clinic Medical Group

3811 Valley Centre Dr, MS S99

San Diego, CA 92130

(858) 764-9010

 

ANESTHESIOLOGY

Todd Allen Austin, MD [4]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

George A Brooker, DO [2]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Christopher William Cary, MD [11]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Nina Chaya, MD [3]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Chien-Hsiang Chow, MD [2]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Jed Adam Cohn, MD [1]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(650) 723-6412

 

William T Connell, MD [9]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

David Wayne Dockweiler, MD [17]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Branden Michael Engorn, MD [2]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Blake Christopher Fowler, MD [5]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

David Dennis Frankville, MD [4]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Jonathan Joseph Gray, MD [5]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Douglas Preston Grove, MD [5]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Paul James Himaya, MD [3]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Hetal H Hosalkar, MD [6]

Grossmont Surgery Center

8881 Fletcher Pkwy, Suite 100

La Mesa, CA 91942

(619) 698-0930

 

Gloria Wen-Song Hwang, MD [2]

Anesthesia Service Medical Group

3626 Ruffin Rd

San Diego, CA 92123

(858) 565-9666

 

Top Doctors
Features SEPTEMBER 29, 2022

I Will Never Eat Another Apple

Troy Johnson introduces our annual Top Doctors issue and shares his recent waiting room scare

I Will Never Eat Another Apple
jasper-johnson-pub-note.jpg

jasper-johnson-pub-note.jpg

About four weeks ago, Claire noticed a large white spot on the roof of our son Jasper’s mouth—about the size of a nickel. She stuck her finger in there, tried to see if it was food or one of the many nonsensical objects that naturally migrate into childrens’ mouths.

It didn’t budge. She brought him to me in a panic. I tried to get my finger in there to dislodge it. Felt hard, but didn’t budge or rub off. Over the next few days, family and friends tried. This white spot was part of him.

With a child at Jasper’s stage of development—nine months old, eight teeth, strong jaw, and strong opinions about adults prodding their fingers in his face—it was hard to get a great look at it without him properly freaking out, wailing, biting, calling the cops. We managed to make him laugh, and snapped a blurry pic. Sent it to everyone we knew. A flurry of Google searches revealed he had at least a few dozen diseases.

My dad, a retired dentist who over 50 years saw almost every form of mouth trauma, was stumped. He showed it to other dentists. All of them, baffled. Was it exposed bone? A malformed palate? My dad said he “didn’t think it was malignant, because there’s no inflammation around the edges.” He was right. Jasper’s mouth was just a normal pink little baby mouth. And he remained happy, content, active, never complained when he ate or stuck a remote control in his mouth.

I have a natural optimism. I tend to not freak out until a few independent sources suggest I should lose it. “It’ll probably go away in a couple days,” I offered.

It didn’t go away. The “what ifs” started to eat holes in us. Claire made an appointment with an ear-nose-throat (ENT) specialist. They could see Jasper a week later. That week was a terrible week. Each time Jasper laughed you’d see that spot. So every time he laughed it was an awful mix of joy and terror.

The first ENT specialist was stumped; said he’d never seen anything like it in all his years. He suggested Jasper get an MRI and a CT scan immediately. Claire had a pretty strong hell-no reaction to that advice. She was not going to radiate our son without a second opinion.

jasper-johnson-and-troy.jpg

jasper-johnson-and-troy.jpg

So we went to Rady’s, one of the best children’s hospitals on the planet. The ENT there was fantastic, but he was also stumped. He managed to get his finger in there before being bit, said it merely felt like the roof of Jasper’s mouth. But it wouldn’t budge and no part of it came off when scratched or prodded. Without causing the child undue stress, the best solution was to put Jasper under anesthesia to let the doctors get a good look at it, have it biopsied.

We agreed. At some point, you have to trust the smartest person in the room. Another stretch of days passed between then and the procedure. Each day, Claire aged 27 years. On the day of his procedure, it had been three weeks since this terrible white spot first entered our lives. The nurses and staff were kind and helpful, seemed to intuitively know how to prevent parents from free-falling into madness. We watched as nurses wheeled him into the operating room, which cratered us.

In the waiting room, I saw the other families. Nothing puts your own minor concerns into perspective like standing in the waiting room of a children’s hospital; some families here were going through things I don’t believe I could ever have the emotional fortitude to withstand.

After about ten minutes, the nurse emerged. The doctor was ready to see us. We were ushered into a consultation room. Longest few minutes of our lives. Finally, the doctor entered. He placed a specimen jar on the table. Inside, I could see the white spot.

“It’s a sticker,” he says.

Like a Scratch n Sniff. Or one that identifies “this apple is Gala.” It was the best sticker in the world. One that could fuse in a wet environment, and despite a very active young tongue wiggling about—managed to adhere perfectly to Jasper’s mouth and would not relinquish its job. After weeks of chewing and drinking, it didn’t even dissolve. Even if we had known it was a sticker, we would have had to put Jasper under, because, the doctor said, “it was stuck so well I had to pry it out a bit—it took some work.”

At the news, I start to laugh uncontrollably. The sheer relief. I look at Claire. She gives me a look that clearly states the time for laughing has not yet arrived. I cease and desist.

Later, in the car, she says, “I turned 100 today.”

Jasper was a little tired for the rest of the day, but fine and sticker-free. The next morning, completely happy and his normal self.

The point of this story is, at every step in this process, I was comforted by one thing. As a native San Diegan, seeing the national rankings and reports come out every year—I just know San Diego has some of the best doctors on the planet. Rady’s, Scripps, Palomar, Sharp, UCSD, Kaiser, Tri-City, docs with private practices. At every turn of this emotional roller coaster, I knew that Jasper’s health was safest right here.

The point of this story is also to say there is a sticker company we should all invest in—or burn to the ground.

Troy Johnson

About Troy Johnson

Troy Johnson is the magazine’s award-winning food writer and humorist, and a long-standing expert on Food Network. His work has been featured on NatGeo, Travel Channel, NPR, and in Food Matters, a textbook of the best American food writing.

Top Doctors
Features OCTOBER 28, 2020

Curing the Unknown in a Global Pandemic

How one of San Diego’s prominent health care centers fought their way through the first days of the pandemic

Curing the Unknown in a Global Pandemic
Curing the Unknown / Dr. Sandeep Soni

Palomar Health’s infectious disease specialist and medical director, Dr. Sandeep Soni

Jenny Siegwart

Palomar Health admitted its first COVID-19 patient March 13, only two days after the World Health Organization declared the novel coronavirus a global pandemic. However, at both its Poway and Escondido medical centers, preparation had been ongoing for months. Hospital directors produced coronavirus protocols beginning in January, with a strong focus on treating those infected without letting the illness spread to staff or any other patients in the building. They succeeded.

As of press time, Palomar Health had administered 1,075 positive COVID-19 tests since early February, and admitted 389 patients. Yet not a single patient or staff member contracted the virus while on campus during this time.

Leading the effort was infectious disease specialist and medical director Dr. Sandeep Soni, who, like most first responders, felt personally invested in preventing further spread of the coronavirus. “My wife is a critical care specialist at Palomar Health,” he says. Their biggest concern was “making sure we’re not taking everything home to our family.”

Working closely with Dr. Soni was Valerie Martinez, a nurse with three decades’ experience who serves as Palomar’s infection control officer, directing a team of infection preventionists. “We used to be called ‘infection control personnel,’” she clarifies, “but we changed our name across the US to ‘infection prevention,’ because we want to prevent rather than have to go in and try to control it.”

First priority, says Soni, was to increase the hospitals’ number of negative pressure rooms. These rooms are equipped with ventilation systems that keep airborne contagions isolated by siphoning the air flow through filtered exhaust vents that lead outside the building.

Palomar’s two campuses had 27 such rooms between them at the beginning of the year. But its facilities operations department went to work around the clock to convert an additional 57.

Curing the Unknown / Valerie Martinez

Valerie Martinez, infection control officer at Palomar Health.

Jenny Siegwart

In normal times, negative pressure rooms might isolate patients with tuberculosis, or other well-studied infectious diseases. At this point, very little was known about this coronavirus—the CDC wouldn’t advise that its transmission is primarily airborne until May—and the Palomar team was able to disregard public health guidelines calling for only conditional use of negative pressure rooms. Instead, it isolated every patient possible in this way, primarily on its Escondido campus.

They also required facial coverings for everyone entering the hospital from the outset, “before it was a directive from county public health,” notes Martinez. This early action looks prescient now, due not only to the well-publicized risk of asymptomatic spreaders, but also that of presymptomatic carriers. “You can transmit the virus about 48 hours before you start showing symptoms,” she explains.

But Soni and Martinez didn’t have to act on foresight. They based many of their decisions on their experience with another coronavirus. “We had to go through this when SARS was on the map a few years ago,” Soni says. “We put those protocols in place because they were very similar.”

Year-round, Martinez and her team work closely with the county to identify the presence of viruses and bacteria before they spread. But more immediately, they work with the hospitals’ environmental services staff—its cleaning crews.

While the facilities department worked to keep hospital air free of coronavirus, Maria Zaragoza-Magno and 124 other custodial employees were implementing best practices to eradicate it from surfaces. On a daily basis, they don protective gear and thoroughly sanitize the rooms of COVID-19 patients, including those on ventilators. Zaragoza-Magno and her colleagues already possessed the skills needed to safely clean isolation rooms before the pandemic, and now they’ve taken additional measures, like using oxycide, a specialized disinfectant, on high-touch surfaces like faucet handles, light switches, and call buttons.

Dr. Soni points out that the work of environmental services staff carries as much risk of infection as that of doctors and nurses. “They still have to gear up, gown up, put on N95 masks, and go into that room,” he says. “They’ve stepped up.” From top to bottom, the roughly 700 employees at work in the two Palomar hospitals on any given day have all faced the risk of picking up the illness and taking it home to their families. “I don’t think there’s a group of nurses or physicians who have not worked with COVID-19 patients.”

Since the pandemic started, the number of non-coronavirus patients in the hospital has steeply declined, most likely because people are avoiding seeking treatment due to fear of catching the virus. For better or for worse, this has left specialists from other departments available to step in to help with COVID-19’s myriad complications, from thickening blood (thrombosis) to loss of elasticity in the lungs (fibrosis).

Curing the Unknown / Maria Zaragoza-Magno

Maria Zaragoza-Magno is one of 125 environmental health services workers dedicated to sanitizing the isolation rooms.

Jenny Siegwart

As professional and public understanding of this confounding new illness changed, at times drastically, Soni credits department leaders with helping develop and implement new protocols on the fly. “I think, as a patient, you’re coming into the hospital expecting your physicians to know everything,” he says. “But we were kind of in a no-man’s land.”

A committee of department heads worked together, seven days a week, deliberating over email threads in response to new data and treatment guidance. The pharmacy team fought to secure medications, lab directors sought materials to reduce test result times from days to hours, anesthesiologists implemented plasma transfusion plans, the heads of emergency and critical care kept teams up to date, and the IT staff kept the hospitals’ internal systems updated so providers could successfully order and track shifting courses of treatment.

Soni also lauds the Palomar Health board of directors, who, by May’s end, had spent $4 million to keep the medical centers supplied with materials necessary for both prevention and treatment. In addition to the cost of negative pressure rooms, protective gear, and hard-to-find medications, Palomar Health boosted the number of ventilators on hand from 40 to 160.

Meanwhile, less-invasive treatments have evolved from pursuing unproven long shots (like hydroxychloroquine) to banking on a four-pronged combination supported by the latest research: anti­coagulants to prevent thrombosis; plasma infusions from COVID-19 survivors to accelerate immune system response; the corticosteroid dexamethasone to reduce inflammation; and the go-to antiviral drug remdesivir, which has only recently become readily available to all patients who need it.

As September began, 47 Palomar Health patients had died from COVID-19, so the system stood at an 88 percent survival rate, versus 78 percent in San Diego overall. Soni observes that the results have improved since this spring, but he already has his mind set on the upcoming flu season. “How is your body going to react?” he wonders. “That’s the big unknown right now. That’s what keeps me up at night.”

Nevertheless, Martinez stresses that people who need treatment for ailments other than COVID-19 should feel confident and safe in visiting the hospital. “It is safe to come in,” she says.

 

Studio S JULY 25, 2026

These San Diego Companies Are Driving the Region’s Next Wave of Growth

This month, the 2026 San Diego Business Impact Awards recognized local businesses making an impact in clean energy, biotech, hospitality, and beyond

These San Diego Companies Are Driving the Region’s Next Wave of Growth
Photo Credit: Matt Furman

Renewable energy companies building hundreds of power plants. Biotech startups using artificial intelligence to create personalized medicine for children with rare diseases. Hospitality companies quietly powering thousands of local events. Consumer brands growing from beach-town startups into national businesses. These are the kinds of companies driving San Diego’s economy today, and the businesses recognized at this year’s San Diego Business Impact Awards offer a snapshot of where the region is headed.

Hosted July 23 by San Diego Regional Economic Development Corporation (EDC) and JPMorganChase, the second annual awards event honored four local companies for innovation, growth, and economic impact. More than 100 nominations from San Diego’s middle-market businesses were reviewed by a 10-person judging committee, with winners selected across four categories: startup, early-stage innovator, rising star, and established heavyweight.

Two-time honoree Jimbo Someck, founder of Jimbo’s organic grocery stores, also joined the event for a fireside chat on buying local, supporting emerging brands, and giving back to the community.

“San Diego’s strength comes from its makers and builders—the resilient people who endure great risks and overcome obstacles to build and scale a company,” says Aaron Ryan, San Diego Region Manager and Middle Market Banking at JPMorganChase & Co. “These awards aren’t just recognition; they spotlight the talent, grit, and innovation shaping our region’s future. By celebrating those who create and build, we foster connections and fuel the growth that keeps San Diego thriving.”

Photo Credit: Matt Furman

Building the Infrastructure Behind Clean Energy

Heavyweight honoree SOLV Energy has grown alongside the country’s rapid investment in renewable power. “It’s an exciting time for SOLV Energy as we are experiencing significant growth,” says CEO George Hershman. “The business has doubled over the last year and has almost double-digit growth since its inception.”

The Rancho Bernardo-based company designs, builds, operates, and maintains utility-scale solar and energy storage facilities. Since its founding in 2008, SOLV Energy has built more than 500 power plants.

Growth has translated directly into hiring. About 200 employees work from the company’s local headquarters, including roughly 20 interns. “Our intern program is a big part of the way that we grow our workforce,” Hershman says. “Last year, 43 percent of our interns became full-time employees. We believe San Diego is a great community to build and grow a high-tech infrastructure and technology company because of the incredible workforce—the ability to attract top talent and draw from world-class universities.”

Photo Credit: Matt Furman

Developing Medicine One Patient at a Time

Startup honoree La Jolla Labs is tackling one of medicine’s biggest challenges by developing personalized RNA therapeutics for patients with rare diseases—many of them children with neurological disorders like ALS. Using proprietary artificial intelligence and machine learning tools, the biotech company develops treatments tailored to each patient’s specific genetic mutation.

CEO Tamar Grossman says the recognition reflects how far the company has come despite limited resources. “We’re honored to be recognized for our ability to change and save patients’ lives and turn our lean startup into a clinical company with very minimal resources,” she says.

Grossman credits San Diego’s concentration of research institutions—including UC San Diego, the Salk Institute, and Scripps Research—with creating a pipeline of talent and collaboration. “San Diego is one of the world-leading centers for technology, genomics, and RNA therapeutics,” she says. “We have over 30 RNA therapeutics companies here, and we support each other and help with anything related to drug discovery.”

She says that collaborative spirit extends beyond formal partnerships. “You can walk around Torrey Pines, go into a café, and find colleagues from the industry and have an ad hoc conversation,” Grossman says. “That’s something very unique to San Diego.”

Photo Credit: Matt Furman

Powering San Diego’s Special Celebrations

While Snake Oil Venue Company may not be a household name, chances are many San Diegans have attended one of its events. The early-stage innovator honoree has expanded from beverage catering and mixology consulting into venue management, operating Julep Venue in Mission Hills, Bramble Bay Venue in Imperial Beach, Vesper Venue, the Chapel at Liberty Station, and five outdoor venues throughout Liberty Station—more than 500,000 square feet of event space altogether.

“We do a lot of launch parties for corporations and new products,” says CEO Mike Esposito. “I really like working on the entrepreneur side of things, where new businesses are entering the San Diego market and looking to make a splash.”

Snake Oil has executed more than 16,000 events, employed more than 1,000 people, and partnered with more than 900 local vendors, including caterers, florists, photographers, entertainers, and other hospitality businesses. The company also works with many of San Diego’s nonprofits, museums, and cultural institutions. “We get to celebrate people’s most important moments,” Esposito says. “Whether that’s a wedding, celebration of life, or quinceañera, we’re fortunate to be involved in the community in so many different ways.”

Photo Credit: Matt Furman
Photo Credit: Matt Furman

Growing a Beach-Town Brand into a National Business

Rising star honoree ALOHA Collection is proof that a simple idea can grow into a thriving company. Founded by two roommates who wanted a better way to carry wet swimsuits after a day at the beach, the lifestyle brand has grown into a business while maintaining strong year-over-year growth.

Now headquartered in Carlsbad, ALOHA Collection employs more than 100 people and operates its California flagship store in Encinitas, which is slated for a remodel. With roots in Hawaii, the company is known for its lightweight, splash-proof travel bags that have become a familiar sight on beaches in San Diego and beyond.

“‘Aloha’ is part of our name, but it’s also how we move through the world,” says CEO Lynna Barnard. “It’s how we show up for people, the way we travel, the way we give back.” Since day one, the company has maintained a 5 percent giveback to Hawaii conservation efforts, contributing millions of dollars over the years.

“I think what’s so inspiring about ALOHA Collection, and the founders in particular, is when you dream big, those dreams can come true when you work hard and trust in the universe,” Barnard says. “It’s inspiring to be a role model for other people wanting to start businesses from humble beginnings. Start small and watch it grow.”

Together, businesses like these form a cornerstone of San Diego’s economy—not only through the jobs and revenue they generate—but through the local workers they hire, vendors they support, and investments they make in the region. Their growth doesn’t happen in isolation; it ripples outward, strengthening the broader business community and the people who call San Diego home.

Photo Credit: Matt Furman

Partner Content
Features OCTOBER 28, 2020

San Diego’s Top Doctors 2020

Our annual list, plus stories on fighting the pandemic at Palomar Health, respiratory therapists, nurse support, giving birth while masked, and why you should put your mental health first—ASAP!

San Diego’s Top Doctors 2020
Jenny Siegwart

Palomar Health infection control officer Valerie Martinez, infectious disease specialist and medical director Dr. Sandeep Soni, and environmental health services worker Maria Zaragoza-Magno

Jenny Siegwart

Top Doctors
Partner Content OCTOBER 4, 2019

San Diego’s Top Doctors 2019

A healthy helping of the breakthroughs, milestones, and on-the-rise practices sweeping San Diego's medical community

San Diego’s Top Doctors 2019

San Diego’s Top Doctors 2019

Top Doctors
Partner Content JULY 21, 2026

You….Elevated: San Diego Magazine’s Guide to Aesthetics 2026

San Diego aesthetic medicine providers help you look—and feel—your best

You….Elevated: San Diego Magazine’s Guide to Aesthetics 2026
SDM-SS_ AestheticProcedures_2026

San Diego is home to world-class aestheticians, plastic surgeons, and dermatologists who can help turn back the hands of time and revitalize tired, damaged skin. Enhancing your look is a spectrum. Treatments range from noninvasive procedures like lasers or injectables to the big guns, like a deep-plane facelift—many with better results and less downtime than ever thanks to advanced techniques and technology. Whether you’re a Botox beginner or an aesthetic medical care veteran, San Diego aestheticians and aesthetic medicine providers can help you look and feel like the best version of yourself.

Changes Plastic Surgery & Spa

Changes Plastic Surgery & Spa is San Diego’s premier destination for aesthetic surgery, led by world-renowned plastic surgeon Dr. Michael Rossi. Celebrated for his artistry, precision, and natural-looking results, Dr. Rossi is known for creating customized Mommy Makeovers that help women restore confidence and reclaim their bodies after pregnancy. His expertise also extends to comprehensive post-weight loss body contouring, addressing excess skin and skin laxity with sophisticated surgical techniques tailored to each patient’s unique anatomy and goals. From breast and body rejuvenation to deep plane facelifts and eyelid surgery, every treatment plan reflects Dr. Rossi’s commitment to surgical excellence, personalized care, and transformative results that look as beautiful as they feel.

Cosmetic Laser Dermatology

At Cosmetic Laser Dermatology, the board-certified, internationally acclaimed team has the power to erase 10+ years of aging in a single treatment. The center’s 60+ laser, light, and energy devices do it all—refining texture and tone, calming acne, minimizing pores, and erasing that ill-advised spring break tattoo of yesteryear. Their dermatologists take it further by stacking multiple devices in one session for synergistic results—the philosophy behind their signature Take5 and Take10 treatments, the latter capable of removing a decade-plus of aging in just one visit. Add a full suite of injectables, body sculpting, and vein treatments for every skin type and tone, and it’s no wonder the practice’s medical director was named the #1 cosmetic dermatologist in America by Newsweek two years running.

Cultivé Medical Aesthetic

If it’s subtle, lasting results you’re after, Cultivé Medical Aesthetics has you covered. Cultivé purposely combines aesthetics and wellness. The Bankers Hill practice offers a full menu of services designed to improve skin health and support the three pillars of aesthetic aging: skin tone and texture, volume loss, and laxity. Cultivé offers a wide range of aesthetic treatments, including collagen boosting powerhouse Morpheus8, biostimulators like Sculptra and Radiesse, PRP therapy, laser hair removal, VI peels, and regenerative skincare treatments. They also provide wellness-focused services such as hormone replacement therapy, IV therapy, and medical weight management programs.

Starlite Aesthetics and Wellness 

Starlite Aesthetics and Wellness focuses on enhancing natural beauty through science-backed treatments tailored to each client’s goals. Michelle Langston, MSN, APRN, FNP-BC, founded Starlite on the principle that aesthetic medicine should be precise, personal, and rooted in wellness. The boutique aesthetic practice in La Jolla combines modern medical aesthetics with holistic wellness principles for refined results personalized to each patient. Langston has spent more than a decade honing her skills in advanced injectables, regenerative therapies, and anti-aging care. Starlite offers regenerative therapies rooted in science, promoting skin rejuvenation using a multiple modality approach. Service offerings include RF microneedling, wrinkle relaxers, facial balancing and more.


The “It” List

In the rapidly advancing field of aesthetic medicine, it can be hard to tell what’s worth the hype. Here are some of the latest, most advanced, and most popular options out there.

Morpheus8: This combination of microneedling and radiofrequency (RF) energy activates your skin’s own collagen and elastin without the downtime associated with some
laser treatments. It can be used to reduce wrinkles, tighten skin, improve skin tone, contour the jawline, and minimize acne scars.

Exosome Therapy: This cutting-edge treatment uses protein-packed nanoparticles to trigger repair and rejuvenation at the cellular level. Often used post-microneedling or lasers, exosomes penetrate deep into the skin to stimulate collagen production.

Post-GLP-1 Skin Removal: Rapid fat loss prompted by GLP-1 medications, including semaglutide, tirzepatide, and retatrutide, can leave users with sagging skin. Skilled surgeons can remove excess skin and reshape the figure.

Treatment Stacking: Sometimes it’s the more the merrier when it comes to aesthetic procedures. Combining multiple non-surgical treatments in a single session allows users to address several issues efficiently, with less downtime.

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