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9 Best Mushrooms For Anxiety 

Mushrooms can work wonders for people suffering from anxiety and depression-related issues. Here are the 9 best mushroom supplements you can try.
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Functional mushrooms, like lion’s mane and reishi, among others, have been known to improve how the body responds to stress. Thus, taking a supplement that features functional mushrooms may help you fight stress and improve your overall mental health.

However, finding a supplement that features high-quality functional mushrooms is rather difficult. The market is full of mushroom supplements, with only a few actually offering what they claim, making it difficult for consumers to trust the quality of ingredients and efficacy of these supplements. So, we have independently tested 30+ mushroom supplements for anxiety in the market and made the job easier for you. 

Here are our top 9 recommendations for mushroom supplements for anxiety and depression. We not only list the ingredients and positives, but we also share the probable negatives for each of these supplements. 

Top 9 Best Mushroom Supplements For Anxiety

Keep reading to get a detailed review of the top brands our team of experts picked as the best mushroom supplements for anxiety.

#1. Riti 

Riti is #1 on our list for offering the best mushroom gummies for anxiety and stress-related issues. These gummies are one of the most effective blends in the market and are manufactured using ethically sourced premium quality mushrooms. 

The ingredient blend in these gummies combines 10 different mushroom extracts, including lion’s mane, shiitake, chaga, maitake, cordyceps, turkey tail, black fungus, white button, and royal sun.

Each mushroom type has a unique benefit to it. 

For example, reishi mushrooms reduce anxiety, boost immunity, and improve the body’s overall vitality. Lion’s mane mushrooms enhance mental clarity and cognitive functions. Collectively, all the extracts in Riti mushroom gummies support nerve function for better attention and focus and show significant potential in modulating mood and response to sudden stress or anxiety. 

The best part about Riti is that they’re transparent and safe, and all their products are third-party lab-tested. Moreover, these mushroom gummies for anxiety come in a natural raspberry flavor and are non-GMO verified. It is gelatin-free and gluten-free. 

The product website suggests using these gummies as a dietary supplement, consuming two gummies daily. Each bottle contains 60 gummies. 


  • 10 different mushroom extract blend
  • Wide spectrum benefits in mental and overall health
  • Enjoyable natural raspberry flavor
  • Ethically sourced premium ingredients
  • Non-GMO, gelatin-free, gluten-free, no artificial color


  • Single flavor variety

=> Click here to visit the official website “Riti”

#2. Cheef Botanicals

Cheef Botanicals is the second brand on our list of the best mushroom supplements for anxiety for its commitment to the quality and purity of mushroom gummies. It offers gummies that aim to help users tackle anxiety and depression issues, along with energy boosts, immunity and focus improvement, and occasional stress management. 

The mushroom gummies by the brand are infused with pure extracts from selected mushrooms like reishi, chaga, lion’s mane, and turkey tail and support immune health, brain, and cognitive functions. 

The best mushroom gummies for anxiety and mental health are available in three types: immunity, brain boost, and wellness. The immunity variant uses extracts from chaga, reishi, and turkey tail and supports immune health. The brain boost variant blends lion’s mane and reishi mushroom extracts. Lion’s mane mushroom extracts often treat oxidative stress and related disorders. That’s because it contains compounds like phenol that have antimicrobial properties. Ultimately leading to reduced or limited cellular and neurological damage, especially in cases of diseases like Parkinson’s and Alzheimer’s.    

At the same time, the wellness type is a more balanced one that combines lion’s mane, chaga, reishi, cordyceps, and turkey tail to offer a comprehensive approach to well-being. 

The functional mushrooms used in these gummies fall into two categories: adaptogenic and nootropic. While the adaptogens in these mushrooms help in managing stress and anxiety, the nootropics aid cognitive functions like memory, focus, and mood. 

These are small and bite-sized and come in various flavors to suit all kinds of palates. Apart from being super-delectable in taste, these mushroom gummies for anxiety come pre-dosed, meaning you get a consistent dosage, and are also convenient to incorporate into your daily health regime. Further, these gummies are vegan-friendly and, hence, suit all diets. 

The recommended dosage is one gummy per day, and it should be used for at least 90 days to see results.


  • Three different blends and targeted formulations for specific needs
  • High-quality mushroom extracts
  • Natural and vegan-friendly
  • Tasty fruity flavors and bite-sized for easy consumption
  • Pre-measured dosage


  • Customers complain about the taste and efficacy
  • Poor customer support

=> Click here to visit the official website “Cheef Botanicals”

#3. CBDfx

CBDfx mushroom supplement for anxiety is the next brand on our list of the most unique blends of supplements. The CBDfx mushroom supplements incorporate the calming effects of CBD with the health benefits of 7 different mushrooms for an overall health upliftment. 

Also, these mushroom gummies have an extensive ingredient list, including mushroom extracts from chaga, lion’s mane, cordyceps, turkey tail, maitake, reishi, and shiitake. Most of these mushrooms have either adaptogenic or nootropic properties. That simply means it improves your thinking skills and makes you feel more alert, making these the best mushroom supplements for anxiety.  

For example, maitake in this blend lends nutrients like vitamins B and C, copper, and other minerals like potassium, amino acids, fiber, and beta-glucans. Cordyceps is extremely high in several B vitamins like B1, B2, K, B12, etc. The shiitake mushroom extract has both nootropic and adaptogenic properties, which help manage physical and mental health and enhance cognitive functions like creativity, motivation, and memory. The adaptogenic properties in these mushrooms, reishi, lion’s mane, and chaga, also help maintain homeostasis (or balance) in the body. 

Apart from the mushroom extracts, each gummy in the bottle contains about 25mg of CBD, which is known to help in relaxation and stress relief. The gummies come in a natural cherry flavor, providing a smooth texture and taste without artificial additives and flavors. The recommended serving is two gummies for adults.


  • An innovative blend of 7 different mushroom extracts
  • 25mg CBD in each capsule for improving stress relief and relaxation
  • No artificial colors or flavors
  • A tasty natural cherry flavor
  • Customers have also noticed reduced back pain and spasms
  • Users are also impressed with improved anxiety and sleep
  • Vegan-friendly


  • Only single flavor variety is available

=> Click here to visit the official website “CBDfx”

#4. Elm & Rye

Elm & Rye creates high-quality, pure, ethically sourced products. Not only do these are one of the best mushrooms that help with anxiety and offer numerous health issues, but they also come in various forms, like capsules, gummies, and coffee creamers. 

This mushroom complex combines functional mushrooms like maitake, lion’s mane, shiitake, reishi, cordyceps, and chaga to give you extensive benefits in overall physical and mental health. It also contains other ingredients in each of the three variants: glucose syrup, pectin, citric acid, sodium citrate, natural flavor, and vegetable oil. 

These blends synergistically provide various health benefits, like supporting the immune system and enhancing cognitive functions, apart from improving overall wellness. 

These gummies and capsules are suitable only for adults, with a recommended dosage of one capsule or gummy per serving. However, the product website does not mention the exact number of gummies or capsules in each bottle. 


  • Blends several functional mushrooms for maximum efficacy 
  • Available in different forms – capsules, gummies, creamers
  • Suitable for overall physical and mental health
  • Quality assured with lab test results available on the website


  • Specific capsule/gummy count not provided

=> Click here to visit the official website “Elm & Rye”

#5. SUKU Vitamins

If you want a versatile option in mushroom supplements, the 5th brand on our list – SUKU Vitamins, is your go-to product. Super mushroom gummies by the brand are packed with nutrition and flavor. These mushroom gummies for anxiety combine four functional mushrooms: reishi, chaga, lion’s mane, and turkey tail. 

These espresso-flavored mushrooms are known for their adaptogenic properties, aiding immune health and cognitive functioning. So, these supplements can be excellent for anyone looking to include a natural and immune-boosting supplement in their routine. 

The reishi mushroom extract used in these supplements helps restore a person’s balance. It can help individuals suffering from depression adapt to different psychological as well as biological stresses. It is assumed to be promising in treating insomnia, paranoia, alcoholic dependence, and OCD, and also reduces psychological distress and suicidal tendencies. 

Moreover, these mushroom supplements for anxiety are great if you’re looking for gluten and sugar-free options. They are also non-GMO, non-allergic (no dairy, nuts, soy, egg, etc.), and free from artificial colors. So, even individuals with dietary restrictions can incorporate these gummies into their daily regime. 

Each bottle contains 60 gummies. The official website says the recommended dosage is two gummies per day with food and should be stored in dry conditions under 15-25 degrees Celsius. Like other gummies, the SUKU Vitamins supplement also requires consistent usage to show results. 


  • Tasty espresso flavor 
  • Combines four potent functional mushroom extracts
  • Vegan and keto-friendly
  • Free from any artificial additives and colors
  • 30-days money back guarantee


  • It may have a diuretic effect, which may not be suitable for all users.

=> Click here to visit the official website “SUKU Vitamins”

#6. Real Mushrooms 

Real Mushrooms is known for its 100% organic mushroom extracts, making it one of the most reliable brands for buying mushroom supplements for anxiety. These supplements are made of reishi mushrooms, a core ingredient in the blend extracted using the dual extraction method with alcohol and hot water. 

Reishi mushrooms are renowned for their potential benefits in reducing stress and boosting immune health. They contain 25% beta-glucans, which is a highly potent compound, and over 4% triterpenes, ensuring maximum efficacy in treating symptoms of hopelessness, anxiety, and depression. 

Using resihi mushrooms for anxiety as the main component, these capsules offer a super-potent and effective solution to manage stress, anxiety, and depression-like symptoms. Other ingredients include hypromellose (vegetable capsule), microcrystalline cellulose, silicon dioxide, and may also contain stearic acid. 

The Real Mushrooms reishi capsules are free from starch, mycelium, and any kind of grain fillers to retain the potency of the mushroom extract. It’s also gluten-free, non-GMO, and vegan-friendly. 

There are two size options available to buyers – 90 and 200 capsule bottles and the recommended dosage is two capsules daily. So, if you’re new to mushroom supplements, you can opt for the smaller size and then move to the bigger one if it is effective.


  • 100% organic reishi mushrooms
  • Non-GMO, gluten-free, vegan
  • No added fillers like starch and grains
  • Rich in beta-glucans and triterpenes
  • Dual extraction process for maximum potency


  • Poor customer support service

=> Click here to visit the official website “Real Mushrooms”

#7. Oweli 

Oweli Shrooms has been the top choice of many for supplements supporting immune health, stress management, cognitive function, and overall brain health, and thus, it finds a place on our list of best mushroom supplements for anxiety. 

This mushroom supplement for anxiety is a holistic blend of 10 functional mushroom extracts, including lion’s mane, reishi, cordyceps, shiitake, maitake, turkey tail, chaga, royal sun, white button, and black fungus. Ethically sourced and scientifically formulated, these ingredients maintain the highest quality. 

Most of these mushrooms for anxiety have adaptogenic properties, making them the right choice for anyone looking for supplements for anxiety and depression. These capsules can potentially improve how the body responds to sudden stress and alleviate extreme problems. 

Unlike caffeine and other conventional stimulants, the adaptogens in chaga mushrooms regulate the metabolism in your body and also trigger reduced effects of stress and depression. The same is true with turkey tail mushrooms due to the high content of vitamin B6, which slows down the brain’s activity.

Apart from these main extracts, the blend contains cellulose, microcrystalline cellulose, and magnesium stearate. Each bottle contains 30 capsules; the recommended dosage for adults is two daily. If unsatisfied with the results, the brand offers a 100-day bottom-of-the-bottle refund guarantee.


  • A blend of 10 functional mushroom extracts
  • Reduces anxiety and signs of depression
  • Improves cognitive and immune health
  • Manufactured in FDA-registered facilities and CGMP-compliant
  • 100-day money-back guarantee


  • Individual results may vary. 

=> Click here to visit the official website “Oweli”

#8. NutriFlair

The NutriFlair mushroom supplement is an impressive blend of 10 functional mushrooms offering improved mental clarity and focus. 

The supplement blend includes mushroom extracts like cordyceps, lion’s mane, chaga, reishi, turkey tail, maitake, shiitake, oyster, enoki, and Agaricus. These are the mushrooms good for anxiety management and popular for their distinctive benefits in aiding mental health and overall well-being. 

Each mushroom supplement for anxiety contains 2600 mg of extract combined from all of these different mushrooms. However, the official website provides information only on the concentration of the three main ingredients – reishi, cordyceps, and lion’s mane mushrooms. The other mushroom extracts are provided in a proprietary blend.  

Moreover, studies show that lion’s mane mushroom extract is beneficial for anxiety and depression only with a minimum dose of 3000 mg per day, which is far from the 800 mg provided in this supplement. 

The mushroom supplements for anxiety are non-GMO, gluten-free, dairy-free, and vegan and have no artificial colors or added sugar.  But despite the rich ingredient list and popularity of the NutriFlair mushroom supplements, it’s often considered less effective than the others on the list. 

Per the brand’s official website, each bottle contains 30 capsules; the suggested use is 3 capsules per day with a meal. 


  • Specifically, it targets brain and immune health
  • Vegan, non-GMO, gluten-free, no artificial colors or added sugar
  • All natural ingredients
  • Users have noticed improved mental clarity and energy
  • People have also seen improved emotional stability and mood


  • No information about third-party lab test results on the website

               #9. Nootrum 

Nootrum mushrooms are one of the most affordably priced supplements available now. Nootrum’s mushrooms for anxiety are formulated using a unique blend of extracts from reishi, cordyceps, lion’s mane, shiitake, maitake, chaga, turkey tail, royal sun, Agaricus, black fungus, and white button mushrooms. It’s a powerful combination of the most commonly used mushrooms in indigenous healing practices across the world. 

These medicinal mushroom extracts, along with ingredients like amanita, L-theanine, and ginger, offer enhanced relief from stress, anxiety, and depression-related problems. Moreover, these ingredients also provide benefits like boosted immunity, better focus, lower inflammation levels, and better mental clarity. 

Apart from improving cerebral blood flow and enhancing stamina, you’ll see a noticeable improvement in sleep and focus. So, if you need help building a stronger immunity or improving memory skills, the Nootrum mushrooms will be a great buy. 

Each bottle contains 30 servings, and it’s recommended to consume 2 gummies daily. 


  • Multiple mushroom extracts for optimum health benefits
  • Improves cognitive functions like memory and focus
  • Provides immune-boosting benefits
  • Free from any artificial additives


  • There is no flavor mentioned on the official website. 

What Are Mushroom Supplements? 

Mushroom supplements for anxiety are nothing but dried and milled whole mushrooms packaged in different forms like powders, pills, gummies, or even liquid tinctures. 

The main ingredient in these supplements is mushroom extract. Made from fruiting bodies, mycelium, or sometimes even whole mushrooms, the supplements are designed to offer a small and more concentrated dose of this bioactive compound. 

While some mushroom varieties are known to offer greater benefits in boosting immunity, others encourage nerve growth and treat anxiety. Some of the most common mushroom varieties used in supplements are reishi, lion’s mane, cordyceps, chaga, shiitake, turkey tail, and psilocybin (hallucinogenic). 

Benefits Of Taking Mushrooms For Anxiety

Although mushrooms have been used for their potential medicinal benefits since as long as 450 BC, it is yet to be scientifically validated by the U.S. Food and Drug Administration (FDA). However, many have been using mushroom pills for anxiety and have noticed a significant improvement in their condition over time. 

Some of the major benefits people have noticed include:

  • Reduced depression and anxiety
  • Improved cognitive function
  • Mood regulation
  • Better sleep and relaxation

Research says that certain mushroom compounds interact with the chemicals in our brains. For example, the psilocybin variety of mushrooms has hallucinogenic compounds that are similar to the serotonin compound in our brains. 

Many believe it is likely to increase anxiety and depression, but it has been shown to have long-lasting benefits in improving them. It acts on the serotoninergic system of our body to restore the serotonin levels that are associated with mood and anxiety. 

What Are The Best Mushroom Supplements For Anxiety & Depression? 

Almost all types of mushrooms are known to provide some health benefits, be it improving immunity or gut health. But, not all of them are beneficial in treating anxiety and depression. 

The best mushrooms for anxiety and depression are:

Reishi Mushroom for Anxiety

These are often called the “mushroom for immortality”. The reason is its stress-relieving and immune-boosting properties. The triterpenes (sedative compounds) in these mushrooms have calming properties working on the nervous system to improve sleep quality and promote relaxation. These triterpenes often interact with the GABA (Gamma-Aminobutyric acid) pathway, an inhibitory neurotransmitter responsible for neural activity in the brain and promoting sleep. 

Reishi mushroom for anxiety are also highly potent adaptogens, meaning they can regulate the stress hormones in our bodies. This directly helps balance the cortisol and adrenaline levels, which modulates how our body reacts to stress and aids it in overcoming it faster. 

Lion’s Mane Mushroom for Anxiety

It’s one of the most researched mushroom varieties for its potential benefits in treating anxiety and depression. It improves mood regulation by preventing the decrease of serotonin and dopamine, which directly affects anxiety in humans. These mushrooms’ erinacine content (bioactive compound) also supports brain functions and nerve growth. 

Lion’s mane mushrooms are believed to reduce loss of nerve growth due to stress and anxiety. It is also considered a potential alternative medicine to protect against Alzheimer’s and other cognitive impairment diseases. 

Cordyceps Mushroom for Anxiety

Caterpillar mushrooms or cordyceps mushrooms are a collective of 400+ species. Many animal and preliminary human studies show that cordyceps are mushrooms good for anxiety. Its compounds may help in energy-boosting and potentially modulate the body’s response to stress. 

One species in the group of cordyceps mushrooms is cordyceps miliaris. It is used in many supplemental tonics for its possible benefit in treating neurological disorders like anxiety and epilepsy. Like reishi mushrooms for anxiety, cordyceps also have adaptogenic properties that help resist mental fatigue and stress by modulating the adrenal glands. 

Can Mushrooms Help With Anxiety? 

Yes, certain mushrooms can potentially help with anxiety. 

Numerous studies point to how microdosing of mushrooms can significantly improve depression and reduce feelings of hopelessness. It also shows a potential improvement in mood and overall cognitive function across different age groups and genders. Mushrooms like lion’s mane have been greatly beneficial in preventing the decrease of serotonin and dopamine levels and also in mediating after-effects like antidepressants. 

But it’s also necessary to approach this with a balanced view. That’s because although there has been some promising research, there is yet to be any scientific conclusive evidence for it. 

Factors To Consider Before Buying Mushrooms That Help With Anxiety

People who want to include mushroom supplements for anxiety in their health regime should consider the factors below to make an informed decision.

Mushroom Types:

Not all mushrooms help with anxiety and depression. So, when choosing the supplement, understand and check its mushroom type. For example, reishi mushrooms have calming properties, while lion’s mane helps improve mood, and cordyceps are for stress resistance. 


The dosage is as important as the ingredient in the mushroom supplement for anxiety. It also depends on the severity of the health issues you’re facing. So, it’s ideal to follow the dosage recommended on the product label or consult a healthcare professional before opting for one. Keep in mind that while overdosing can have adverse effects, underdosing may seem like the product is ineffective.


Always check if the mushrooms are sourced and third-party tested. Check for pure extracts and additives that may dilute the product’s efficacy. Look for where the mushrooms are sourced from on the brand website or the product label. Also, check for any ingredient you may be allergic to. 

Brand Reputation:

Always opt for established brands with good footing in the market when going for the best mushrooms for mental health and anxiety. That’s because such brands will have rigorous testing and quality control procedures. You can also check the brand website to know the manufacturing process and commitment to safety. 


Quality is THE most important aspect to look for in mushroom supplements for anxiety. Good quality mushroom supplements will have third-party test results. You can also look for indicators like organic, non-GMO, and sustainably sourced products. 

Customer Reviews

Go through product reviews on e-commerce platforms as well as brand websites. E-commerce platforms offer real insights into the product’s efficacy, potential side effects, and the overall impact on users. 

How Many Mushrooms Should You Take For Anxiety? 

For any mushroom supplement for anxiety and depression, the dosage depends on many factors. Like the concentration of the extract, the type of mushroom, the formulation of the product, and most importantly, the health condition you’re facing. So, it’s always best to consult a professional for a personalized regime or follow the recommended dosage guidelines on the product packaging. 

A word of advice: if you’re new to mushroom supplements for anxiety, always start with a low dose. Observe and understand how your body reacts to the supplement, and then you can gradually increase the dosage if required. 

FAQs About Mushrooms For Anxiety And Depression

Q1. How do anxiety and depression affect the body?

Depression and anxiety are serious medical conditions that not only affect the body but also the quality of life you lead. Apart from symptoms like overwhelming grief or guilt, it can severely impact the digestive, cardiovascular, and immune systems. Some common effects include recurring pain, fatigue, poor appetite, insomnia, and even a decreased drive for sex. 

Q2. How to take mushrooms for anxiety & depression?

Most medicinal mushrooms require consistent use over a period to be able to show effects on anxiety and depression. Ideally, you should allow at least three months for the daily regime to deliver results. Although, you can expect to see improvements during the period itself. For the dosage, you can follow the instructions on the product label. 

Q3. What are the potential side effects of using mushrooms for anxiety?

Although mushrooms that help with anxiety are safe for consumption, they do have some potential side effects like itchiness, diarrhea, dry mouth, and gastrointestinal issues. It can also show allergic reactions in some people. Moreover, these supplements may interact with other medications like medicines for blood pressure and diabetes.  

Q4. How long does mushroom for anxiety take to work?

Our bodies react differently to supplements. So, the time mushroom supplements take to help with anxiety differs for each one of us. Factors like metabolism, severity of symptoms, lifestyle, period of use, diet, and even the type of mushroom supplement you’re taking play a role. Generally, it can take a few weeks to a few months to show results. 

Q5. Can you take mushroom supplements with other anxiety medications?

It’s important to understand that some mushroom supplements for anxiety can affect how other drugs or medicines are metabolized in your body. Some mushroom supplements can also amplify the effects of other anxiety medications, potentially leading to over-sedation. So, if you’re already on antidepressants or other medicines, you should check with a healthcare professional before opting for supplements. 

Concluding Thoughts: What Mushrooms Are Good For Anxiety?

Medicinal mushrooms offer a range of health benefits, especially for people suffering from anxiety, poor mood levels, and depression. But the efficacy also largely depends on the product’s quality, extraction, and formulation. So, it’s key to finding the right brand that uses ethically sourced and high-quality mushroom pills for anxiety. 

Among all the mushroom supplements for anxiety we tested, we found Riti’s supplements stand out in quality and efficacy. They are transparent in their approach and use premium quality ingredients that ensure they’re safe and you get value from your investment. 
Note: If you’re already on medication for any ailments, always check with a healthcare professional before introducing mushroom gummies for anxiety to your daily routine.

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